Austin Daye had 22 points and Tim Duncan added 19 as the Spurs earned their 14th straight win with a 113-91 victory Monday night that sent the 76ers to their 25th consecutive loss.
Philadelphia will face Houston on Thursday with the dubious distinction of being a loss shy of tying the NBA record for consecutive losses set by the Cleveland Cavaliers in 2010-11.
Kawhi Leonard and Patty Mills scored 15 points each and Cory Joseph added 12 for San Antonio, which maintained the league's best record at 54-16.
Thaddeus Young and Michael Carter-Williams each scored 19 points, Byron Mullens added 15 and Elliot Williams had 14 for Philadelphia (15-56).