No. 16 Florida could be without point guard Kasey Hill for a month, maybe longer.
Hill suffered a high-ankle sprain in a 67-53 victory against Southern on Monday night. Coach Billy Donovan said team doctors are "pretty confident right now there's nothing broken."
The Gators had little trouble without Hill against the Jaguars (1-4).
Casey Prather had 10 points and nine rebounds, one of three players in double figures, as the Gators extended their home winning streak to 18. Florida led by 16 at halftime and cruised from there.
Calvin Godfrey led Southern with 18 points and nine rebounds. Trelun Banks added 12 points.