The short-handed Spurs hung in, but Alan Anderson scored 19 of his 22 points in the second half to lead the Brooklyn Nets to a 103-89 victory Thursday night.
Despite playing without Tony Parker, Tim Duncan, Manu Ginobili and Kawhi Leonard, their top four scorers, the Spurs were still within five points early in the fourth quarter before the Nets pulled away for good.
Deron Williams added 16 points and eight assists as Brooklyn ended a six-game losing streak to San Antonio with its first victory since March 29, 2010.
Cory Joseph scored 18 for the Spurs, Danny Green had 17 and Patty Mills 16.