Naadir Tharpe scored 21 points for Kansas, and Frank Mason stripped Oklahoma State's Le'Bryan Nash as the final buzzer sounded to preserve the 15th-ranked Jayhawks' 80-78 victory over the ninth-ranked Cowboys on Saturday.
Joel Embiid added 13 points, 11 rebounds and eight blocks for the Jayhawks (13-4, 4-0 Big 12), who blew most of a 47-30 halftime lead before holding on at the finish.
Phil Forte hit seven 3-pointers and had 21 points for Oklahoma State (15-3, 3-2). Marcus Smart added 16 points, but he was just 3 of 14 from the field and 0 for 6 from behind the 3-point arc.