Washington jumped to a 14-point lead midway through the first half before UConn responded, with Shabazz Napier scoring 15 of his 20 points in the second half to lead Connecticut to an 82-70 victory.
Connecticut (10-1) was coming off its first loss of the season, 53-51 to Stanford at home Wednesday.
C.J. Wilcox hit two straight 3-pointers to give UW a 31-17 lead with 7 minutes to go in the first half, but those shots seemed to wake up the visiting Huskies.
UConn answered with a 15-2 run, including a stretch of 10 straight points.